Quote of the Day

By the 1990s, state action had been responsible for the violent or unnatural deaths of some 125 million people during the [20th] century, more perhaps than it had succeeded in destroying during the whole of human history up to 1900. 

Paul Johnson in Modern Times

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How Common Is Celiac Disease?

Celiac disease, aka gluten enteropathy, affects one of every 133 Americans, according to the National Digestive Diseases Information Clearinghouse.  That’s much more common than we thought a couple decades ago.  Read about celiac disease symptoms and physical signs at About.com or the NDDIC link.

I read a few paleo diet/lifestyle blogs regularly.  In case you didn’t know, paleo diet advocates shun wheat and other grains.  Recent paleo converts often report how this or that symptom or physical condition improved when the dieter “went paleo,” often attributing the improvement to cutting out wheat products.   Wheat contains a protein—gluten—that causes disease in people who have celiac disease.  Other sources of gluten are barley and rye.

Visit WebMD for details about celiac disease: http://www.webmd.com/digestive-disorders/celiac-disease/default.htm

Click to see one definition of the paleo diet: http://paleodiet.com/definition.htm

An article in the Wall Street Journal implies that star tennis player Novak Djokovic’s recent winning streak is attributable to a gluten-free (and low-carb) diet.  Click for details: http://online.wsj.com/article/SB10001424052748703509104576327624238594818.html 

Here are Dr. Barbara Berkeley’s thoughts on Djokovic: http://refusetoregain.com/refusetoregain/2011/08/novak-djokovic-the-diet-that-conquered-tennis.html

Or is Djokovic playing so well because of the CVAC pod?: http://online.wsj.com/article/SB10001424053111904787404576532854267519860.html

If cutting out wheat from your diet improves or resolves bothersome medical symptoms, it makes me wonder if you have celiac disease.  Other possible explanations include placebo effect and coincidence.  And if you switch from a standard American diet to paleo, you’re doing more than just eliminating gluten.

I reviewed several sources for the prevalence of celiac disease in the U.S.  The best figure is one of every 133 residents. 

Most countries have a prevalence of roughly one of every 350 citizens.  Prevalence varies by country and ancestry; celiac disease is at least twice as common in whites of northern European lineage.

Full-blown classic celiac disease is relatively easy for doctors to recognize, but that’s only the tip of the iceberg.  Adults more commonly have one or two milder, nonspecific manifestations such as fatigue, malaise, depression, malnutrition (especially low iron, folate, or vitamin D), neuropathy, belly pain, headaches, thin bones, diarrhea, or a rash.  I’m glad to see increasing physician and public awareness of gluten intolerance.  If it’s not considered as a cause of these symptoms, it’ll never be diagnosed and treated appropriately.

Celiac disease is being diagnosed more often because of the availability of blood tests that help us screen for it.  If you think you have celiac disease, consider getting one of two blood tests: IgA antibodies to tissue transglutaminase, or IgA endomysial antibodies.  If that test is positive and symptoms or physical signs suggest celiac disease, the next step is usually a small bowel biopsy.

Steve Parker, M.D.

Update August 31, 2011: Tom Naughton reviewed Dr. William Davis’ new book, Wheat Belly, yesterday.  In the book, Dr. Davis notes that modern wheat varieties are vastly different from their ancient ancestors, different even than wheat of 50 years ago.  The modern varieties apparently contain much more of the gluten proteins that trigger immunologic celiac symptoms. 

Update September 13, 2011: A recent study of adult type 1 diabetics at a U.K. teaching hospital found celiac disease in three of every hundred cases.

References: WebMD.com (about one in a hundred US residents affected), University of Chicago Celiac Disease Center (one in 133 Americans affected), and MedicineNet.com (one in 3000 (sic) North Americans affected), UpToDate.com (in most countries, one in 350 have celiac disease), National Digestive Diseases Information Clearinghouse (one in 133 in U.S.).

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Mediterranean Diet Ranks No.2 Overall

US News and World Report a couple months ago ranked 20 popular diets for weight loss, overall healthfulness,  and diabetes and heart disease management.  Overall best diet was awarded to the DASH diet. Mediterranean came in No.2. 

The Mayo Clinic has free info on the DASH diet.  Here’s my definition of the Mediterranean diet.

Steve Parker, M.D.

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Book Review: Sugar Nation – The Hidden Truth Behind America’s Deadliest Habit and the Simple Way to Beat It

I recently read Sugar Nation, by Jeff O’Connell, published in 2011.  Per Amazon.com’s rating system, I give it five stars (“I love it”). 

♦   ♦   ♦

With the U.S. Centers for Disease Control predicting that one of every three citizens born in 2000 will become diabetic, this book is “just what the doctor ordered.”  Already,  one in three of all adults has prediabetes.  The numbers are even scarier if we look at those over 65: HALF have prediabetes, while two in ten have diabetes.  I treat diabetes every day; trust me, you don’t want it.

I agree with O’Connell that over-consumption of sugar and refined starches often leads to type 2 diabetes and prediabetes, particularly when combined with obesity, a sedentary lifestlye, and genetic predisposition.  (Our bodies easily and quickly convert potatoes and refined starches like white flour and white rice into blood sugar.) Yearly sugar consumption in the U.S. was five pounds per person in the 1800s, but is now up to 160 pounds a year. 

O’Connell was motivated to write this because of his personal diagonosis of prediabetes in 2006.  Later he was also diagnosed with reactive hypoglycemia.  Furthermore, his father died of the ravages of type 2 diabetes.  O’Connell’s physician in 2006 didn’t offer much managmement advice, so the author did his own research and shares it with us here.  The author’s personal approach has been a fairly intense exercise program and major reduction in consumption of sugar and other carbohydrates, particularly ones that are quickly converted to blood sugar.  He eats 80 or less grams of carb daily, compared to the average American’s 275 grams.  I agree these management options can be extremely helpful for prediabetes and type 2 diabetes, particularly if applied early in the course of the condition.

O’Connell is critical of most physicians and the American Diabetes Association (ADA) for not knowing about carbohydrate restriction and for inadequately promoting exercise.  He accuses the pharmaceutical industry of having too much influence over physicians and the ADA.  While admitting that “…taking a pill [is] much easier than reengineering the way you lead your life,” he mostly lets patients off the hook in terms of taking control of diet and physical activity.  I can understand that to a degree; physicians should be leading the way.  I don’t see that happening soon.  Patients need to take charge now; many have already done so.  Compared to a five-minute lecture in a doctor’s office, this book will be a much more effective motivator for change.

(Patients taking drugs with the potential to cause hypoglycemia need their doctors’ help adjusting dosages while making these lifestyle changes.)

The author tells us that we in the U.S. spent $12.5 billion on drugs for diabetes in 2007, nearly double the amount spent in 2001.  It’s only going to get worse going forward.  We have 11 classes of drugs for diabetes now.  Surprisingly, we don’t know all of the potential adverse long-term side effects of most of these drugs.  Phenformin was pulled from the U.S. market years ago due to fatal lactic acid build-up.  Earlier this year, rosiglitazone prescribing was greatly restricted in view of adverse heart effects.  If we can effectively address diabetes and prediabetes with diet and exercise, why not?  (Clearly, diet and exercise don’t always work, and type 1 diabetics always need insulin.) 

For those who won’t or can’t exercise regularly, be aware that carb restriction alone is a powerful approach.

I heard more about reactive hypoglycemia a couple decades ago than I do now.  It could be a precursor to type 2 diabetes.  I think physicians lost interest in it because too many people were using it as a excuse for odd behavior when they really didn’t have hypogylcemia.  This book may spark a resurgence in interest.

O’Connell implies that the high revenues generated by diabetic drug manufacturers may not be justifiable.  In fairness, I must point out that the same companies spend hundreds of millions of dollars just to get a drug on the market, and millions more on research for drugs that fail and never see the light of day.

I was glad to see the author mention low-carb beers: Michelob Ultra and MGD 64.  I’ve had trouble finding carb counts on many beers.

O’Connell recommends supplements: leucine, cinnamon, protein powder, chromium, alpha lipoic acid, biotin, magnesium.  I’ve not done in-depth research on most of those.  What I’ve read in the science literature about cinnamon and chromium has not been very positive or definitive.

My favorite sentence: “Along with a low-carb eating plan, a gym memership is the most potent antidote to type 2 diabetes.”  Nevertheless, don’t let this turn you off; you can do the essential exercise without a gym membership.

This book was a pleasure to read; professional, well-organized, touching all the right bases in understandable terms.  I can well understand how he makes a living as a journalist. 

Steve Parker, M.D., author of Conquer Diabetes and Prediabetes: The Low-Carb  Mediterranean Diet   

Disclosure: I don’t know the author.  The publisher’s representative provided me with two free copies of the book, otherwise I recieved nothing of value in exchange for this review.  I gave one of the books to a contest-winner at my Advanced Mediterranean Diet blog.  The contest was to be the first reader to e-mail me with the name for “wisps of precipitation streaming from a cloud but evaporating before reaching the ground.”

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Save $3 on Book

For readers of my blogs, I’m offering a $3.00 (USD) discount off the usual retail price for Conquer Diabetes and Prediabetes: The Low-Carb Mediterranean Diet.  You probably won’t find a better price anywhere—$13.95 plus shipping.  To get the discount, you have to order from CreateSpace and enter this discount code when you order:

9V9B6FML

This is a time-limited offer, so make your decision within the next few days.

The book is available (without the discount) at Amazon.com, which also offers the Kindle edition.  Other e-book formats are available at Smashwords for $9.99 (USD).

If those are all too expensive, explore the Diabetic Mediterranean Diet blog; most of the information is scattered herein.  If you have diabetes or prediabetes, I want you to have this valuable information.

Steve Parker, M.D.

PS: I also authored an award-winning weight-loss book based on the traditional Mediterranean diet, The Advanced Mediterranean Diet: Lose Weight, Feel Better, Live Longer.  For folks with diabetes or prediabetes, Conquer Diabetes is the better choice.

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Quote of the Day

The disillusion with socialism and other forms of collectivism, which became the dominant spirit of the 1980s, was only one aspect of a much wider loss of faith in the state as an agency of benevolence.  The state was, up to to the 1980s, the great gainer of the twentieth century; and the central failure.

Paul Johnson in his book,  Modern Times

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Quote of the Day

“It is easier to change a man’s religion than to change his diet.”

Margaret Mead

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Everything You Ever Wanted to Know About Olives But Were Afraid to Ask…

Olives and olive oil are iconic components of the the Mediterranean diet.  Nutrition Diva Monica Reinagel has a wonderful post about olives and olive oil.  What are the best olives to eat?  How are olives processed?  Are olives more heathful than olive oil?  Click through for the answers.

-Steve Parker, M.D.

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What About Triglycerides?

 

Great source of marine omega-3 fatty acids

Circulation recently published the American Heart Association Scientific Statement: Triglycerides and Cardiovascular Disease.  I’ve not read the full document, but here are a few tidbits I’ll share:

  • Triglycerides (TGs) are not direclty atherogenic; they are a biomarker for cardiovascular risk
  • Optimal fasting TGs are under 100 mg/dl (1.1 mmol/l)
  • Normal nonfasting TGs are under 200 mg/dl (2.3 mmol/l)
  • If levels are high, treatment focuses on intensive therapeutic lifestyle change
  • To reduce high TGs, diet modifications include reduction of “simple carbohydrates” like added sugars and fructose by replacing with unsaturated fats, implementing a Mediterranean-style diet, reduction of saturated fat and trans fat consumption, increased marine omega-3 fatty acid intake
  • To reduce high TGs in the setting of overweight and obesity, aim for loss of 5 or 10% of body weight
  • To reduce high TGs, do aerobic exercise at least twice weekly

From my quick scan, I didn’t see much effort to push drugs on people with triglycerides under 500 mg/dl (5.6 mmol/l).

Thanks to Circulation for making this available to the public at no charge.

Steve Parker, M.D.

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Quote of the Day

 Science-Based Medicine published a recent post on the state of American Psychiatry and mental illness.  It’s well worth a look if you’re interested in such things.  Here’s a quote:

The tally of those who are so disabled by mental disorders that they qualify for Supplemental Security Income (SSI) or Social Security Disability Insurance (SSDI) increased nearly two and a half times between 1987 and 2007—from one in 184 Americans to one in 76.”

Do you believe many mental illnesses are caused by a chemical imbalance in the brain?  It’s such a time-saver for the physician to tell the inquiring patient, “You just have a chemical imbalance.  This drug will help straighten it out.”  Read the post for counter-arguments.

Steve Parker, M.D.

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