Category Archives: Weight Loss
Probably. Also probably not a good idea to fly solo, without personal medical attention.
Here’s a link to details of the diet, which has reversed some cases of type 2 diabetes, prepared by Professor Roy Taylor. Overall, his advice looks pretty reasonable to me. However, with such severe calorie restriction (600-800 cals/day), I think a multivitamin supplement might be a good idea.
Note that Taylor says any reasonable diet that leads to loss of enough excess weight may be just as good as the Newcastle diet.
The Joslin diabetes blog has an interesting article on brown fat and its effect on metabolic rate and insulin sensitivity. Brown fat is just a type of body type different from the more plentiful white fat (which is actually more pale yellow). If there are other colors of body fat, I don’t know.
If you can “activate” your brown fat, it helps you burn more calories, which could be helpful if you’re trying to lose weight. It also improves insulin sensitivity: beneficial if you have type 2 diabetes or are prone to it.
“When brown fat is fully activated, it can burn between 200 and 300 extra calories per day. It is most successfully activated through cold exposure. A recent study of people with type 2 diabetes had volunteers sit in a 50 degree room for a couple of hours a day for 10 days in shorts and short-sleeved shirts.
“When I say cold, it’s not icy cold, it’s not like the winter in Boston,” she says. “It’s more or less like the temperature we have here in autumn. After this mild cold exposure, all ten volunteers with type 2 diabetes, as shown in that study, displayed increased brown fat activity and improved insulin sensitivity. This is very exciting.”
Dr. Tseng is working on understanding exactly what is happening on a cellular level to activate brown fat in the cold to see if she can create a drug that will mimic the effects. “Although cold works, it’s just not pleasant,” she says. “If you had to sit in a cold room for a few hours every day, perhaps not everybody could accept that.”
Another way to activate brown fat is exercise (at least if you’re a man or a mouse).
Steve Parker, M.D.
…in terms of weight loss, lowering of HgbA1c, and weight-related quality of life. The specific gastric bypass surgery used in the study is the Roux-en-Y version.
Average initial weight of participants was 104 kg (229 lb). Bypass patients dropped their weight by 25 kg (55 lb)and HgbA1c decreased by 1.8% (absolute decrease), compared to intensive medical management participants who lost 10.3 kg (32 lb) and dropped HgbA1c only by 0.4%.
I doubt that intensive medical therapy included a low-carb Mediterranean or paleo diet.
Source: Clinical and Patient-Centered Outcomes in Obese Patients With Type 2 Diabetes 3 Years After Randomization to Roux-en-Y Gastric Bypass Surgery Versus Intensive Lifestyle Management: The SLIMM-T2D Study | Diabetes Care
To improve your odds of success, read my series on preparing for weight loss.
Seems to be, at least for some folks who are overweight. Nine of 10 T2 diabetes are overweight or obese
The “cure” at hand involves reduction of daily calories to 800 for four weeks. Average weight loss of those in the experimental group was 10 kg (22 lb). I look forward to the published scientific journal report. I bet the drop-out rate was high.
Yet another good post from DietDoctor! Why fast? Among many reasons is that fasting turns on autophagy, which helps clear the debris of daily living out of your cells, probably leading to longer life.
Click here for P.D. Mangan’s post on fasting and autophagy.
Dr. Fung at DietDoctor also warns about the danger of hypoglycemia for certain folks with diabetes. Read that part carefully (click the Source link below).
Anyway, here are Dr. Fung’s top eight tips (direct quotes):
- Drink water: Start each morning with a full eight-ounce glass of water.
- Stay busy: It’ll keep your mind off food. It often helps to choose a busy day at work for a fast day.
- Drink coffee: Coffee is a mild appetite suppressant. Green tea, black tea, and bone broth may also help.
- Ride the waves: Hunger comes in waves; it is not continuous. When it hits, slowly drink a glass of water or a hot cup of coffee. Often by the time you’ve finished, your hunger will have passed.
- Don’t tell anybody you are fasting: Most people will try to discourage you, as they do not understand the benefits. A close-knit support group is often beneficial, but telling everybody you know is not a good idea.
- Give yourself one month: It takes time for your body to get used to fasting. The first few times you fast may be difficult, so be prepared. Don’t be discouraged. It will get easier.
- Follow a nutritious diet on non-fast days: Intermittent fasting is not an excuse to eat whatever you like. During non-fasting days, stick to a nutritious diet low in sugars and refined carbohydrates.
- Don’t’ binge: After fasting, pretend it never happened. Eat normally, as if you had never fasted.
Steve Parker, M.D.
PS: I don’t feature fasting in any of my books, but I’ve gradually come around to seeing the potential benefits.