Tag Archives: diabetic mediterranean diet

Recipe: Pico De Gallo

According to Wikipedia, pico de gallo is Spanish for rooster’s beak. I always thought it was peck of the rooster, because it’s got some bite to it. You decide how spicy you want it based on how much jalapeño you use. Also note that one batch of jalapeños is different in heat from the next.

paleo diet, Steve Parker MD, diabetic diet

Our rooster, Chuck: handsome but mean!

Pico de gallo is a condiment that compliments eggs, meat, and guacamole, to name a few. I throw it in a bowl of soup sometimes. Save any you don’t eat in the ‘frig, but eat it within three days.

Ingredients:

  • tomatoes, fresh, 7 oz (200 g), chopped very finely
  • onion, fresh, 2 oz (60 g), chopped very finely
  • jalapeño pepper, fresh, 1 whole (14 g), chopped very finely after discarding stem
  • cilantro, fresh, 10–15 sprigs chopped finely to yield 3–4 tbsp (2 g)
  • salt, 2 pinches (2/16 tsp) or to taste

Instructions:

If you prefer less spicy heat, use less jalapeno and don’t use the seeds. Combine all ingredients and you’re done. Eat at room temperature, chilled, or heated at medium heat in a saucepan (about 5 minutes, until jalapenos lose their intense green color).

Servings: 3 servings of 1/2 cup (120 ml) each.

Nutritional Analysis Per Serving:

  • 8% fat
  • 81% carbohydrate
  • 11% protein
  • 21 calories
  • 4.5 g carbohydrate
  • 1.2 g fiber
  • 3.3 g digestible carbohydrate
  • 104 mg sodium (2 pinches of added salt)
  • 216 mg potassium
paleo diet, Steve Parker MD, pico de gallo

Some prefer it coarsely chopped like this – it’s quicker

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Book Review: Diabetes Solution – The Complete Guide to Achieving Normal Blood Sugars

Here’s my review of Dr. Bernstein’s Diabetes Solution: The Complete Guide to Achieving Normal Blood Sugars, published in 2007.  Per Amazon.com’s rating scale, I give it five stars (I love it).  

♦   ♦   ♦ 

Dr. Richard K. Bernstein gives away thousands of dollars’ worth of medical advice in this masterpiece, Diabetes Solution.  It’s a summation of his entire medical career and a gift to the diabetes community.  

The book starts off with some incredible testimonials: reversal of diabetic nerve damage, eye damage, and erectile dysfunction.  They’re a bit off-putting to a skeptic like me, like an infomercial.  Dr. Bernstein is either lying about these or he’s not; I believe him.  His strongest testimonial is his own.  He’s been a type 1 diabetic most of his life, having acquired the disease at a time when most type 1’s never saw 55 candles on a birthday cake.  He’s in his mid-70s now and still working vigorously.  

I only found one obvious error and assume it’s a misprint. He writes that 95% of people born today in the U.S. will eventually develop diabetes.  That’s preposterous.  The U.S. Centers for Disease Control predicts that one in three born in 2000 will be diagnosed.  

Dr. Bernstein delivers lots of facts that I can neither confirm nor refute.  He’s a full-time diabetologist; I am not.  

"Put down the bread and no one will get hurt!"

  

The central problem in type 1 diabetes is that, due to a lack of insulin,  ingested carbohydrates lead to spikes (elevations) in blood sugar.  The sugar elevations themselves are toxic.  The usual insulin injections are not good imitators of a healthy pancreas gland. So Dr. Bernstein is an advocate of low-carb eating (about 30 g daily compared to the usual American 250-300 g).  He says the available insulins CAN handle the glucose produced by a high-protein meal.  

Dr. B reminds us that insulin is the main fat-building hormone, which is one reason diabetics gain weight when they start insulin, and why type 2 diabetics with insulin resistance (and high blood insulin levels) are overweight and have trouble losing weight.  You can have resistance to insulin’s blood sugar lowering action yet no resistance to its fat-building (fat-storing) action.  Insulin also stimulates hunger, so insulin-resistant diabetics are often hungry.  

“Carbohydrate counting” is a popular method for determining a dose of injected insulin.  Dr. B says the gram counts on most foods are only a rough estimate—far too rough.  He minimizes the error by minimizing the input (ingested carbs).  From his days as an engineer, he notes “small inputs, small mistakes.”  

Dr. B also cites problems with the absorption of injected insulin.  Absorption is variable: the larger the dose, the greater the variability.  So don’t eat a lot of carbs that require a large insulin dose.  For adult type 1 diabetics, his recommended rapid-acting insulins doses are usually three to five units.  If a dose larger than seven units is needed, split it into different sites.  

He recommends diabetics aim for normal glucoses (90 mg/dl or less) almost all the time, and hemoglobin A1c of 5% or less.  This is extremely tight control, tighter than any expert panel recommends.  He says this is the best way to avoid the serious complications of diabetes.   

Here’s a smattering of “facts” in the book that made an impact on me, a physician practicing internal medicine for over two decades.  I want to remember them, incorporate into my practice, or research further to confirm:  

  • Hemoglobin A1c of 5% equals an average blood sugar of 100 mg/dl (5.56 mmol/l).  For each one % higher, average glucose is 40 mg/dl (2.22  mmol/l) higher.
  • He’s against any drugs that overstimulate (“burn out”) the remaining pancreas function in type 2 diabetics: sulfonylureas, meglitinides, “phenylalanine derivatives”.  Pancreas-provoking agents cause hypoglycemia and destroy beta cell function.
  • The insulin sensitizers are metformin and thiazolidinediones.  He likes these.
  • Blood sugar normalization in type 2 diabetes and early-stage type 1 can help restore beta cell function.
  • He often speaks of preserving beta cell function.
  • He believes in “insulin-mimetic agents” like alpha lipoic acid (especially R-ALA, and take biotin with either form) and evening primrose oil.  These  are no substitute for insulin injections but allow for lower insulin doses.  ALA and evening primrose oil don’t promote fat storage like insulin does.
  • He says many cardiologists take ALA for its antioxidant properties [news to me]
  • He says rosiglitazone works within two hours [news to me] but later admits it may take 12 weeks to see maximal benefit
  • One of his goals is to preserve beta cell function if at all possible
  • He prefers rosiglitazone over pioglitazone due to fewer drug interactions
  • “Americans are fat largely because of sugar, starches, and other high-carbohydrate foods.”
  • He’s convinced that people who crave carbohydrates have inherited the problem, which also predisposes to insulin resistance and type 2 diabetes.  Low-carb diets decrease the cravings for many, in his experience.
  • In small amounts, alcohol is relatively harmless: dry wine, beer, spirits.  Very few doctors have the courage to say this.
  • If you’re in a restaurant, you can use urine sugar test strips and saliva to test for presence of sugar or flour in food
  • A rule of thumb: one gram of carbohydrate will raise blood sugar about 5 mg/dl (0.28  mmol/l) or less for most diabetic adults weighing 140 lb (64  kg) and about 2.5 mg/dl (0.139 mmol/l) in a 280-pounder (127  kg).  This must refer to type 1 diabetics or a type 2 with little residual pancreas beta cell function; variable degrees of insulin resistance and beta cell reserve in many type 2s would make this formula unreliable.
  • Be wary of maltodextrin in Splenda: it does raise blood sugar.
  • Much new to me in his section on artificial sweeteners.  Be wary of them.
  • He avoids all grains, breads, crackers, barley, oats, rice, and pasta.
  • Most diet sodas are OK.
  • Coffees with 1-2 tsp milk is OK.  Cream is OK.
  • He eats NO fruit and recommends against it.
  • He avoids beets, corn, potatoes, and beans. A slice of tomato in one cup of salad is OK.  A small amount of onion is OK.
  • String beans and snow peas are OK.
  • Cooked vegetables tend to raise blood sugar more rapidly than raw.
  • Use “Equal” aspartame tabs as a sweetener.  Don’t use “powdered” Splenda.
  • Avoid nuts: too easy to overeat.
  • For desert: sugar-free Jell-O Brand Gelatin.
  • Yogurt?  Plain, whole milk, unsweetened.  Flavor with cinnamon, Da Vinci syrups, baking flavor extracts, stevia or Equal.
  • Avoid balsamic vinegar.
  • Need fiber?  Bran crackers or soybean products.
  • “Ideally, your blood sugar should be the same after eating as it was before.”  85 mg/dl (4.72  mmol/l) is his usual goal.  If blood sugar rises by more than 10 mg/dl (0.56 mmol/l) after a meal, either the meal has to be changed or medication changed.
  • Protein is a source of glucose: keep protein amounts at meals constant from day to day, especially if taking glucose-lowering drugs.
  • The lowest-carb meal of the day should be breakafast.  Why?  Dawn phenomenon.
  • He promotes strenuous, prolonged exercise, especially weight training (extensive discussion and instruction in book).
  • Many diabetics on insulin need dose adjustments in 1/2 and 1/4 unit increments [news to me: if I ordered 4 and 1/4 units of insulin at the hospital, the nurses would laugh].
  • Typical rapid-acting insulin doses for his adult type 1 patients are 3-5 units.  The “industrial doses” of insulin seen or recommended by many physicians reflect diets too high in carbohydrate.
  • He says Lantus only acts for nine hours (nighttime injection) or 18 hours (AM injection).
  • He doesn’t like mixed insulins (e.g., 70/30).
  • Humalog and Novolog are more potent than regular insulin, so the dose is about 2/3 of the regular insulin dose
  • “Only a few of the 20 available [home glucose monitoring] machines are suitably accurate for our purposes.”  “None are suitably accurate or precise above 200 mg/dl [11.11 mmol/l].”
  • Vitamin C in doses over 250 mg interferes with fingertip glucose monitors.  Later he says doses over 500 mg cause falsely low readings.
  • He prefers regular insulin (45 minutes before meal) over Novolog and Humalog, because of its five-hour duration of action.
  • Insulin users need to check glucose levels hourly while driving.
  • His personal basal insulin is 3 units Lantus twice daily.
  • He urges use of glucose (e.g., Dextrotabs) to correct hypoglycemia.
  • He says hypoglycemia is rare on his regimen.
  • He has an entire chapter on gastroparesis.

Dr. Bernstein’s recommended eating program in a nutshell:  

  • Some similarities to the Atkins diet, which he never mentions.
  • No simple sugars or “fast-acting” carbs like bread and potatoes, because even type 2s have impaired or nonexistent phase 1 insulin response.
  • Limit carbs to an amount that will work with your injected insulin or your remaining phase 2 insulin response, if any.
  • “Stop eating when you no longer feel hungry, not when you’re stuffed.”
  • Follow a predetermined meal plan (each meal: same grams of carb and ounces of protein)
  • Six g (or less) of carbs at breakfast, 12 g (or less) at lunch and evening meal.  So his patients count carb grams and protein ounces.
  • Supplements are not required IF glucoses are controlled and eating a variety of veggies.  Otherwise you may need B-complex or multivitamin/multimineral supplement.
  • Recipes are provided.

His has four basic drug treatment plans, tailored to the individual.  They are outlined in the book.  Dr. B provides detailed notes on what he does with his personal patients.  

Overall impressions:  

  • Too complicated for most, and they won’t give up higher carb consumption.  It requires a high degree of committment and discipline.  In fact, I’ve never had a patient tell me they were on the Bernstein program.
  • If I had type 1 diabetes, I might well follow his plan or the Low-Carb Mediterranean Diet, NOT the high-carb diet recommended by the ADA and many dietitians.
  • And if I had type 2 diabetes?  Low-Carb Mediterranean Diet first, Diabetes Solution as second choice.
  • If one can get his hemoglobins A1c down to 5% with other methods, would that be just as good?  Dr. B would argue that all other methods have blood sugar swings that are too wide.
  • Many new ideas and techniques here, at least to me.
  • He pretty much reveals his entire program here, which is priceless.
  • I’m not sure this plan will work unless the patient’s treating physician is on-board.
  • His personal testimony and breadth of knowledge are very persuasive. 

Steve Parker, M.D.  

Disclosure:  I was given nothing of value by Dr. Bernstein or his publisher in return for this review.

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Filed under Book Reviews, Carbohydrate, Drugs for Diabetes, Protein

Low-Carb Mediterranean Diet Improves Glucose Control and Heart Risk Factors in Overweight Diabetics

In overweight type 2 diabetics, a low-carbohydrate Mediterranean diet improved HDL cholesterol levels and glucose control better than either the standard Mediterranean diet or American Diabetes Association diet, according to Israeli researchers reporting earlier this year.

Background

Prior studies suggest that diets rich in monounsaturated fatty acids (olive oil, for example) elevate HDL cholesterol and reduce LDL cholestrol and triglycerides in type 2 diabetics.

Low-carb diets improve blood sugar levels and reduce excess body weight in type 2 diabetics, leading to the ADA’s allowance in 2008 of a low-carbohydrate diet as an alternative to standard diabetic diets.

Many—probably most—type 2 diabetics have insulin resistance:  the body’s cells that can remove sugar from the bloodstream are not very sensitive to the effect of insulin driving sugar into those cells.  They “resist” insulin’s effect.  Consumption of monounsaturated fatty acids  improves insulin sensitivity.  In other words, insulin is better able to push blood sugar into cells, removing it from the bloodstream.

Previous studies have shown that both low-carb diets and the Mediterranean diet reduce after-meal elevations in blood sugar, which likely lowers levels of triglycerides and LDL cholesterol.

How Was the Study Done?

The goal was to compare effects of three diets in overweight type 2 diabetics in Israel over the course of one year.  Study participants totalled 259.  Average age was 56, average weight 86 kg (189 lb), average hemoglobin A1c 8.3%, and average fasting plasma glucose (sugar) was 10.3 mmol/L (185 mg/dl).  [Many diabetics in the U.S. fit this profile.]  People taking insulin were excluded from the study, as were those with proliferative diabetic retinopathy—no reasons given. 

Participants were randomly assigned to one of three diets, so there were about 85 in each group.  [Over the course of one year, people dropped out of the study for various reasons, leaving each group with about 60 subjects.] 

Here are the diets:

  • 2003 ADA (American Diabetes Association) diet:  50-55% of total caloric intake from carbohydrate (mixed glycemic index carbs), 30%  from fat, 20% from protein
  • Traditional Mediterranean (TM):  50-55% low-glycemic-index carbs, 30% fat—high in monounsaturated fat, 15-20% protein
  • Low-carb Mediterranean (LCM) :  35% low-glycemic-index carbs, 45% fat—high in monounsaturated fat, 15-20% protein

Patients were followed-up by the same dietitian every two weeks for one year.  All were advised to do aerobic exercise for 30-45 minutes at least three days a week.

Olive oil is traditionally the predominant form of fat in the Mediterranean diet and is a particularly rich source of monounsaturated fat.  At no point in this report was olive oil mentioned, nor any other source of monounsaturated fat.  Until I hear otherwise, I will assume that olive oil was the major source of monounsaturated fat in the TM and LCM diets. 

 All diets were designed to provide 20 calories per kilogram of body weight. 

In all three diets, saturated fat provided 7% of total calories.  Monounsaturated fatty acids provided 23% of total calories in the LCM, and  10% in the other two diets.  Polyunsaturated fatty acids provided 15% of calories in the LCM, and 12% in the other two diets.  The ADA diet provided 15 grams of fiber, the TM had 30 g, and the LCM had 45 g.

Adherence to the assigned diet was assessed with a “food frequency questionnaire” administered at six months.

What Did the Researchers Find?

Average reported energy intake was similar in all three groups: 2,222 calories per day.

Monounsaturated fat intake differences were statistically significant: 14.6, 12.8, and 12.6% for the LCM, TM, and ADA diets, respectively.  Polyunsaturated fat intake differences were statistically significant: 12.9, 11.5, and 11.2% for the LCM, TM, and ADA diets, respectively.

Percentage of energy from carbs was highest for the ADA diet (45.4%), intermediate for the TM diet (45.2%), and lowest for the LCM diet (41.9%).

At the end of 12 months, all three groups lost about the same amount of weight (8-9 kg or 18-20 lb), body mass index, and waist circumference.

Hemoglobin A1c fell in all three groups, but was significantly greater for the LCM group than for the ADA diet (6.3% absolute value vs 6.7%).

Triglycerides fell in all three groups, but was significantly greater for the LCM diet compared to the ADA diet.

The LCM group achieved a significant increase (12%) in HDL cholesterol compared to the ADA diet, but not different from the TM group.

LDL cholesterol fell in all three groups, and the LCM group’s drop (25%) was clearly superior to that of the ADA diet (14%) but about the same as the TM diet (21%).

Conclusions of the Investigators

We found that an intensive community-based dietary intervention reduced cardiovascular risk factors in overweight patients with [type 2 diabetes] for all three diets.  The LCM group had improved cardiovascular risk factors compared to either the ADA or the TM groups.

Only the LCM improved HDL levels and was superior to both the ADA and TM in improving glycaemic control.

It would appear that the low carbohydrate Mediterranean diet should be recommended for overweight diabetic patients.

My Comments

There’s no way the average diabetic could replicate this low-carb Mediterranean diet without working closely with a dietitian or nutritionist.

Any superiority of this low-carb Mediterranean diet may have as much to do with the increased monounsaturated fat intake as with the reduced carb consumption.  Monounsaturated fatty acid consumption is thought to improve insulin sensitivity. 

NutritionData’s Nutrient Search Tool can give you a list of foods high in monounsaturated fat.

The Mediterranean diet and low-carb diets independently have been shown to lower after-meal glucose levels, which probably lowers LDL cholesterol and triglycerides.

I’m disappointed the dietitians were not able to achieve a lower level of carbohydrate consumption in the low-carb Mediterranean diet group.  I suspect if they had, improvements in glucose control and lipids would have been even better.  But proof awaits another day.

We saw last year an article in the Annals of Internal Medicine that showed a dramatic reduction in the need for glucose-lowering drugs in type 2 diabetics following a different low-carb Mediterranean diet over four years, compared to a low-fat American Heart Association diet.  These two studies convince me a low-carb Mediterranean diet has real life-preserving and life-enhancing potential. 

Diabetics looking for a low-carb Mediterranean diet today have several options:

If you’re aware of any other low-carb, explicitly Mediterranean-style diets, please share in the Comments section.

Steve Parker, M.D. 

References: 

Elhayany, A., Lustman, A., Abel, R., Attal-Singer, J., and Vinker, S.  A low carbohydrate Mediterranean diet improves cardiovascular risk factors and diabetes control among overweight patients with type 2 dabetes mellitus:  a 1-year prospective randomized intervention studyDiabetes, Obesity and Metabolism, 12 (2010): 204-209.

Esposito, Katherine, et al.  Effects of a Mediterranean-style diet on the need for antihyperglycemic drug therapy in patients with newly diagnosed type 2 diabetesAnnals of Internal Medicine, 151 (2009): 306-314.

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Filed under Carbohydrate, coronary heart disease, Fat in Diet, Glycemic Index and Load, Mediterranean Diet, olive oil

Legumes and Whole Grains: Any Role in Diabetes?

Expert nutrition panels consistently recommend whole grains and legumes for people with diabetes.  Why?  And do these foods affect development of diabetes?  I found a pertinent scientific review article on the subject from 2004 in the European Journal of Clinical Nutrition.  Here are some pertinent quotes from the summary:

Epidemiological studies strongly support the suggestion that high intakes of whole grain foods protect against the development of type II diabetes mellitus (T2DM). People who consume approximately 3 servings per day of whole grain foods are less likely to develop T2DM than low consumers (<3 servings per week) with a risk reduction in the order of 20-30%.

The role of legumes in the prevention of diabetes is less clear, possibly because of the relatively low intake of leguminous foods in the populations studied. However, legumes share several qualities with whole grains of potential benefit to glycaemic control including slow release carbohydrate and a high fibre content. A substantial increase in dietary intake of legumes as replacement food for more rapidly digested carbohydrate might therefore be expected to improve glycaemic control and thus reduce incident diabetes. This is consistent with the results of dietary intervention studies that have found improvements in glycaemic control after increasing the dietary intake of whole grain foods, legumes, vegetables and fruit.

. . . it is cereal fibre that is largely insoluble [rather than soluble fiber] that is associated with a reduced risk of developing T2DM.

Thus, there is strong evidence to suggest that eating a variety of whole grain foods and legumes is beneficial in the prevention and management of diabetes. This is compatible with advice from around the world that recommends consumption of a wide range of carbohydrate foods from cereals, vegetables, legumes and fruits both for the general population and for people with diabetes.

Gluten Intolerance

A major protein in wheat is gluten.  The last few years have seen the popular emergence of gluten-free this and gluten-free that.  The idea is that gluten causes a variety of gastrointestinal, immunologic, and other problems, so wheat products should be avoided.  Certainly they should be avoided in people with celiac disease, a well-established medical condition.  I follow a few paleo blogs and know that grains and legumes are not part of that way of eating: the paleos say we are not evolved optimally to process them.    

If legumes or wheat or other grains cause problems for you, don’t eat them.  They have no essential nutrients that you can’t get elsewhere. 

Glycemic Index

In my quest to develop a healthy Diabetic Mediterranean Diet, I’m finding that grains—compared to nearly all other carbohydrate-containing food groups—tend to have a higher glycemic index (GI).   A low GI is 55 or less.  High GI is 70 or greater.  Grains in general raise blood sugar levels higher than many other sources of carbohydrates.  But this is highly variable and depends partially on preparation of the grain.  Whole grain products have a lower GI than highly processed counterparts.  For instance, white bread has a GI of 70; whole wheat bread 67.  Regular spaghetti is 38.  Table sugar’s GI must be sky high, right?  No, its just 61.  A baked potato is a whopping 85.   

Beans have a GI around 30 or 40.  And they pack a lot more fiber per serving.  For a diabetic struggling to keep blood sugars under control, which is a better choice: grains or legumes?  I’m leaning towards legumes and other components of a low-glycemic-index diet.   

Steve Parker, M.D.

PS:  [Before you correct my GI numbers, please note I’m  aware that various GI lists don’t agree with each other.]

Reference:  Venn, B.J. and Mann, J.I. Cereal grains, legumes and diabetes.  European Journal of Clinical Nutrition, 58 (2004): 1,443-1,461.

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Filed under Fiber, Fruits, Grains, legumes, Prevention of T2 Diabetes, Vegetables