Do You Really Need to Restrict Salt Consumption?

Unfairly demonized?

The American Council on  Science and Health has a brief review of the latest research on salt restriction, and it’s not supportive of population-wide sodium restriction.  On the other hand, salt-restriction proponents believe it would reduce strokes, heart attacks, heart failure, and premature death.  I’ve been a salt-restriction skeptic for a couple decades.

Remember, table salt molecules contain one sodium atom and one chloride atom.  Salt-restricted and low-sodium diets are usually designated by the amount of sodium, not salt.

That being said, I do believe some individuals have elevated blood pressure related to relatively high sodium intake.  This may apply to one of every five adults with high blood pressure.  To find out if you’re one of the five, you could go on a low-sodium diet—1.5 to 3 grams a day—for one or two months and see what it does to your blood pressure.  Get your personal physician’s blessing first.

Steve Parker, M.D.

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Happy Thanksgiving!

Godspeed = May God prosper you

It’s a wonderful holiday for my U.S.A. readers, started by the Pilgrims in 1621.

Godspeed,

—Steve

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Is Your Blood Sugar Meter Accurate?

David Mendosa reviewed some reviews on home blood glucose monitor accuracy and reproducibility.  He was motivated by a recent review in Consumer Reports.  You’ll want to click through his links for details.  The last time I looked into this, I learned that a device could receive FDA approval if it could measure accuracy to within 20% of the actual blood sugar value as determined by a laboratory machine.  For a blood sugar of 200 mg/dl (11.1 mmol/l), the home device could give you a value anywhere between 160 and 240 mg/dl (8.9 to 13.3 mmol/l).  That doesn’t exactly inspire confidence, does it?

—Steve

 

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What Causes Type 2 Diabetes?

“Beats me. I teach math!”

I have no simple answer for you, unfortunately.

You can lower your risk of type 2 diabetes significantly by avoiding overweight and obesity, by exercising regularly, and by choosing the right parents.  These provide clues as to the causes of diabetes.  The Mediterranean diet also prevents diabetes.

UpToDate.com offers a deceptively simple answer:

Type 2 diabetes mellitus is caused by a combination of varying degrees of insulin resistance and relative insulin deficiency. [Insulin is the pancreas hormone that lowers blood sugar.] Its occurrence most likely represents a complex interaction among many genes and environmental factors, which are different among different populations and individuals.

So, what causes the insulin resistance and relative insulin deficiency?

Understanding the pathogenesis [cause] of type 2 diabetes is complicated by several factors. Patients present with a combination of varying degrees of insulin resistance and relative insulin deficiency, and it is likely that both contribute to type 2 diabetes. Furthermore, each of the clinical features can arise through genetic or environmental influences, making it difficult to determine the exact cause in an individual patient. Moreover, hyperglycemia itself can impair pancreatic beta cell function and exacerbate insulin resistance, leading to a vicious cycle of hyperglycemia causing a worsening metabolic state.

The UpToDate article then drones on for a several thousand words discussing mouse studies, various genes, free fatty acids, adiponectin, leptin, amylin, insulin secretion, insulin resistance, impaired insulin processing, insulin action, body fat distribution, inflammation, various inflammatory markers, low birth weight, high birth rate, prematurity, etc.  More excerpts:

Increased free fatty acid levels, inflammatory cytokines from fat, and oxidative factors, have all been implicated in the pathogenesis of metabolic syndrome, type 2 diabetes, and their cardiovascular complications.

Insulin resistance may, at least in part, be related to substances secreted by adipocytes [fat cells] (“adipokines” including leptin adiponectin, tumor necrosis factor alpha, and resistin).

Type 2 diabetes most likely represents a complex interaction among many genes and environmental factors.

That’s the simplest answer I can give now.

Steve Parker, M.D.

Reference: “The Pathogensis of Type 2 Diabetes Mellitus”  by David K McCulloch, MD, and R Paul Robertson, MD, at UpToDate.com, updated June 2012, and accessed November 19, 2012.

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QOTD: Homeopathy

I love it when ads for medical remedies claim to be “homeopathic.” That way I know straight away they’re no better than placebo.

Steve Parker, M.D.

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Does Dietary Protein Affect Blood Sugars?

The protein in this can raise your blood sugar

I’m considering whether I should advise my patients with diabetes to pay careful attention to the protein content of their diet, assuming they’re not malnourished.  It’s an important issue to Dr. Richard K. Bernstein, who definitely says it has to be taken into account.

Protein can undoubtedly raise blood sugar levels.  But is the effect clinically significant?  Most  dietitians and physicians pay little attention to it as a source of hyperglycemia.  Here are some of Dr. Bernstein’s ideas pulled from the current edition of Diabetes Solution:

  • The liver (and the kidneys and intestines to a lesser extent) can convert protein to glucose, although it’s a slow and inefficient process.
  • Since the conversion process—called gluconeogenesis—is slow and inefficient, diabetics don’t see the high blood sugar spikes they would see from many ingested carbohydrates.
  • For example, 3 ounces (85 g) of hamburger patty could be converted to 6.5 g of glucose under the right circumstances.
  • Protein foods from animals (e.g., meat, fish, chicken, eggs) are about 20% protein by weight.
  • Dr. B recommends keeping protein portions in a particular meal consistent day-to-day (for example 6 ounces with each lunch).
  • He recommends at least 1–1.2 g of protein per kilogram of ideal body weight for non-athletic adults.  That’s more than the usual 0.8 g per kilogram.
  • The minimum protein he recommends for a 155-lb non-athletic adult is 11.7–14 ounces daily.
  • Growing children and athletes need more protein.
  • Each uncooked ounce of the foods on his “protein foods” list (page 181) provides about 6 g of protein.
  • On his eating plan, you choose the amount of protein in a meal that would satisfy you, which might be 3 ounces or 6–9 ounces.
  • If you have gastroparesis, however, you should limit your evening meal protein to 2 ounces of eggs, cheese, fish, or ground meat, while eating more protein at the two earlier meals in the day.

“In many respects—and going against the grain of a number of the medical establishment’s accepted notions about diabetics and protein—protein will become the most important part of our diet if you are going to control blood sugars just as it was for our hunter-getherer ancestors.”

Conclusions

I haven’t changed my thinking on this issue yet, but will let you know if and when I do.  I don’t talk much about protein in Conquer Diabetes and Prediabetes in part because I wanted to keep the program simpler than Dr. Bernstein’s.  Albert Einstein reportedly said, “Everything should be made as simple as possible, but not simpler.”

As with most aspects of diabetes, your mileage may vary.  The effect of dietary protein on blood sugars will depend on type 1 versus type 2 diabetes, and will vary from one person to another.  So it may be impossible to set rigid guidelines.

If interested, you can determine how much protein is in various foods at NutritionData.

Steve Parker, M.D.

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Dukan Diet Founder Loses Libel Lawsuit Against Dr. Cohen

Dr. Pierre Dukan sued another diet doctor, Jean-Michel Cohen, for claiming that the Dukan diet could harm dieters.  A French court ruled in Dr. Cohen’s favor last year.  U.K.’s The Telegraph has a few of the details. Claire Al-Aufi has more at Hive Health Media.

I reviewed the Dukan diet last April.  Gee, I hope I’m not Dr. Dukan’s next target!

Steve Parker, M.D.

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Filed under Book Reviews, Weight Loss

The History of Insulin

Banting and Best’s experiments on dogs gave us insulin

Dr. Harriet Hall over at Science-Based Medicine reviews the discovery and purification of insulin, truly a modern medical miracle.  One of the first human users was Elizabeth Hughes.

—Steve

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Quote of the Day

Americans could once boast proudly that their system set the benchmark for the world; the United States was the rule of law. But now what we see is the rule of lawyers, which is something different.

Niall Ferguson

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Minimalist Exercise For Those Who Don’t Enjoy It

“Wanna arm wrestle?”

I hate exercising.  Don’t you?

I’d rather watch TV, play Parcheesi, play my mandolin, bowl, go to a movie, sleep, blog, surf the ‘net, work on my next book, fish, visit with my wife and kids, practice shooting, work on new recipes, or even go to work.

But….

I want the health benefits of exercise.

So for much of this year I’ve been experimenting with various exercise programs that may yield the health benefits with minimal time commitment.  Like 60 minutes a week.  Not the 150 minutes recommended by some public health authorities.  In case you’re interested, here are some links that outline the programs:

If you’re tempted to try any of these programs, get your personal physician’s blessing first.  I’d love to hear about your experience with them.

Steve Parker, M.D.

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