Long-Term Severe Carbohydrate Restriction Is Possible!

I got an email a few days ago from a blog reader, J.H. (I won’t give his name because I didn’t ask permission to publish his letter):

Dr. Parker — I’m a 65 year old male who has battled insulin resistance and pre-diabetes for many years. About 15 months ago I started pursuing a very low carb (20 grams per day) ketogenic diet, and my health has improved significantly. I’ve lost about 35 lbs (down from 265), and I have not found it difficult at all to stay on this regimen. You mentioned in an article (https://diabeticmediterraneandiet.com/ketogenic-mediterranean-diet/) that you don’t believe people can stay with it for more than 6 months and that most people can only last about two weeks. With all due respect, hogwash! I was fortunate enough to become a patient of Eric Westman at Duke, and he does an excellent job of teaching the ketogenic diet to his patients. Any overweight person should give it great consideration, and it’s just not that hard to follow.

Best regards, J.H.

My response was: “Congrats on a job well done! I wish all my patients had your discipline and commitment.”

I have great respect for Dr. Westman. He’s the c0-author of The New Atkins for a New You. I reviewed it in 2010. No clinical studies have compared the effectiveness of Dr. Westman’s diet to my Ketogenic Mediterranean Diet, which attempts to lasso the health benefits of the time-honored traditional Mediterranean diet while helping folks lose weight. The Ketogenic Mediterranean Diet is a key component of Conquer Diabetes and Prediabetes.

Steve Parker, M.D.

PS: You don’t have to know what ketogenic means to benefit from ketosis.

PPS: I have a non-diabetic version of the Ketogenic Mediterranean Diet for otherwise healthy folks who just need to lose a boatload of weight.

low-carb mediterranean diet

Front cover of book

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Are These Two Diabetes Drugs Better Than the Others?

Better living through chemistry

Empagliflozin is a pill. Liraglutide is a once-daily subQ injection.

The two drugs in question are empagliflozin (aka Jardiance) and liraglutide (aka Victoza). Both are used to treat type 2 diabetes, not type 1.

A major problem we have with most diabetes drugs is that while they do lower blood sugars, we don’t have much evidence on whether they actually prolong life and prevent bad outcomes like heart attacks, strokes, cancer, blindness, kidney failure, amputations, and serious infections. It gets even more complicated. For instance, a given drug may eventually be proven to prolong life by a year via prevention of death from heart disease, while at the same time increasing the risk of spending that last year bedridden from a stroke.

It’s extremely difficult and costly to suss out these issues. It requires large clinical trials wherein half of the PWDs (people with diabetes) are treated with a particular drug, and the other half are treated with “standard therapy.” Five or 10 years later you compare clinical endpoints between the two groups. A couple studies have done this recently.

A blogger I follow, Larry Husten, wrote the following:

But it was the secondary goal of these trials that led to the transformation of the field. Baked into the trial design was the provision that if they were able to establish noninferiority then the trial investigators were permitted to test for superiority. The second phase began when Empa-Reg became the first trial to convincingly show a clear benefit, including a reduction in cardiovascular death and a reduction in hospitalization for heart failure. with empagliflozin (Jardiance, Merck). Then, more recently, the LEADER trial showed a significant reduction in cardiovascular events with liraglutide (Victoza, Novo Nordisk). In both trials nearly all the patients had significant established cardiovascular disease—precisely the population that cardiologists are likely to see.

Click the embedded links above for more details. Even better, read the original research reports if you have the time and knowledge. I support my family with a full-time job taking care of patients, so it will be a while (if ever) before I can dig into this further. (When my book sales make me independently wealthy, I’ll have more time for this!)

diabetic diet, low-carb Mediterranean Diet, low-carb, Conquer Diabetes and Prediabetes

Analyzing clinical reports requires a good grasp of logic, statistics, and basic science

Are the LEADER and Empa-Reg trials valid? Yeah, maybe. In an ideal world, other investigators would try to replicate the results with additional clinical trials. Are the published results free of fraud and bias? I don’t know.

Because we don’t know the long-term effects of many of our diabetes drugs, I favor doing as much as possible to control blood sugars with diet, exercise, and weight management.

Stay tuned for future developments.

Steve Parker, M.D.

PS: Just because one drug in a class of drugs reduces bad clinical outcomes, it doesn’t mean all drugs in the class do.

PPS: If it’s hard for you to pronounce empagliflozin and liraglutide, some of my books don’t even have them.

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Have You Tried a Sardicado Sandwich?

California or Hass avocado

California or Hass avocado

Several years ago, Alton Brown lost a significant amount of weight, and one of the items on his diet was sardine-avocado sandwiches. I like sardines. I like avocados. But I never ever would have considered eating them mixed together.

A while back, I read Franziska Spritzler’s The Low Carb Dietitian’s Guide to Health and Beauty (great book; my review). One of her recipes involves the sardine-avocado combo, so I’m resolved to give it a try. Her recipe was simply 4 oz (120 g) canned sardines mixed with 1/2 medium avocado and sea salt, stuffed in a large red bell pepper. I bet the sardine-avocado mix would be good on a bed of lettuce if I don’t have a bell pepper. A little black pepper and a squeeze of lemon, too?

If memory serves, I paid $1.29 for this tin of sardines. "Best used by" date is five years from now.

If memory serves, I paid $1.29 (USD) for this tin of sardines. “Best used by” date is five years from now.

I may even try Franziska’s Chocolate Avocado Pudding, another combo I never would have imagined.

Click for Alton Brown’s sardicado sandwich.

Steve Parker, M.D.

PS: If you don’t like the smell of sardines, my books won’t offend your olfactory sense.

low-carb mediterranean diet

Front cover of book

 

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Should You Reduce Saturated Fat Consumption If You Have Heart Disease?

kkk

Most heart attacks occur in folks with pre-existing coronary artery disease that’s been present for years

For the bulk of my medical career, physicians thought that saturated fat caused heart disease, specifically coronary artery disease and heart attacks. Most doctors still think that. In 2009, I spent 80 hours reviewing the scientific literature supporting the saturated fat/heart disease connection. The evidence was very weak, if not nonexistent.

But what if you are already a heart disease patient? Would continuing saturated fat consumption have any effect on your longevity and risk of future heart attacks? If you already have coronary artery disease, Dr. Axel Sigurdsson says that ongoing saturated fat intake probably doesn’t matter, in terms of future cardiac events (like heart attacks) or risk of death from any cause.

Dr. Sigurdsson is a cardiologist in Iceland.

Some quotes from his blog:

For decades, cardiologists have advised patients with heart disease to restrict the intake of saturated fats and dietary cholesterol. Many patients still believe this to be the cornerstone of their lifestyle modification.

The main reason for avoiding saturated fats is the assumption that they adversely affect the lipid profile of our patients.

*   *   *

Recent studies suggest that the recommendation to avoid saturated fats may have been premature and not based on solid scientific evidence.

Now, a recently published Norwegian study shows that dietary intake of saturated fatty acids was not associated with risk of future events or death among patients with established coronary artery disease.

It is important to keep in mind that most of the patients were receiving secondary prevention drug therapy including aspirin, beta blockers and statins.

Anyhow, the results of the study certainly suggest that high intake of saturated fats is not a risk factor among patients with coronary heart disease receiving modern-day treatment.

These recent scientific data don’t imply that we should urge our patients to consume high amounts of saturated fats. They only tell us that there is no association and accordingly, restriction won’t help.

So, it’s certainly a lifeline for those who believe red meat, whole-fat milk, cheese, cream, butter and eggs can be a part of a healthy diet.

On the other hand we must realise that scientific studies often provide contradictory results. A US study published last year suggested that greater adherence to a low carbohydrate diet high in animal sources of fat and protein was associated with higher all-cause and cardiovascular mortality following acute heart attack.

It appears the jury is still out…

RTWT.

Steve Parker, M.D.

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Successful U.K. Rebellion Against Official Diabetic Diet Advice

DailyMail.com has a few of the details. A snippet:

More than 120,000 people signed up to a ‘low-carb’ diet plan launched by the forum diabetes.co.uk in a backlash against official advice.
More than 80,000 of those who ditched a low-fat high-carbohydrate diet found their blood glucose level drop after ten weeks.
By rejecting official guidelines and eating a diet high in protein and low in starchy food – along with ‘good saturated fats like olive and nuts – more than 80 per cent of the patients said they had lost weight.

An article at The Times says, “The results have led doctors to call for an overhaul of official dietary guidelines.”

Regular readers here won’t be surprised by these findings.

The road to this revolution is paved with scientific studies showing that dietary saturated fat has little or nothing to do with causing cardiovascular disease. I crossed that Rubicon in 2009.

If you want the benefits of low-carb eating, check out my free Low-Carb Mediterranean Diet. The book is even better.

Steve Parker, M.D.

PS: If you think carbs are bad, my books have zero net carbs.

low-carb mediterranean diet

Front cover of book

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You Want Long Telomeres, Don’t You?

Judicious wine consumption is one component of the traditional healthy Mediterranean diet

Judicious wine consumption is one component of the traditional healthy Mediterranean diet

Telomeres are very trendy in the biomedical research community. Like kale and chia seeds with hipster foodies.

Telomeres are repetitive chains of amino acids attached to strands of your DNA. The longer your telomeres, the lower your risk of chronic disease and premature death, generally speaking.

The massive Nurses Health Study showed that women who ate a Mediterranean-style diet had the longer telomeres, which is good. That fits with other evidence of greater longevity and lower chronic disease rates in Mediterranean dieters.

Click for a brief pertinent article at NEJM Journal Watch, which includes a link to the original research report.

To lose weight with the Mediterranean diet, check out my book, Conquer Diabetes and Prediabetes: The Low-Carb Mediterranean Diet.

Steve Parker, M.D.

 

PS: If you didn’t know chia pets have their own Wikipedia page, see my other books.

PPS: We don’t know if telomeres are longer in men eating Mediterranean-style

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Book Review: Gorilla Mindset: How to dominate and unleash the animal inside you to live a life of health, wealth, and freedom

 

Gorilla-Mindset-book

Lawyer, blogger, and Tweetmaster Mike Cernovich has a new book, Gorilla Mindset: How to dominate and unleash the animal inside you to live a life of health, wealth, and freedom. Per Amazon.com’s rating system, I give it four stars (I like it).

♦  ♦  ♦

I’m an internal medicine specialist. For years, I’ve been struggling with how to convince my patients to exercise regularly and lose excess weight permanently. Why? So they’ll be healthier and live longer. Everyone wants to do that, right? But so few do. Because it’s hard to change lifelong habits to achieve a goal that may be years away. To make the change, you need the right mindset. Yes, it starts in your head.

The old mindset is: “I’ve been fat and lazy for years. I’ll always be fat and lazy. I’ve tried and failed a dozen times to change my lifestyle, and will fail every time.”

What’s the necessary new mindset? “I can do this. I’m not a brainless automaton without free will. I can see that discipline and sacrifice today will pay priceless dividends down the road. I don’t have to be fat just because everyone in my family is. I can overcome temptation. I’m not going to spend time with losers that bring me down. I’ll make new friends, people who live like me and support me. I will not be brainwashed by advertisers and food manufacturers who are only concerned about their profit, not my life. I have a plan for my life, and being fat and lazy aren’t in it.”

I wish I could download and install that into my patients’ brains!

Who created this?

Who created this?

I read this book hoping to pick up some new tips that would help me with my patients that need that mindset shift. And the author did not disappoint. I also ran across several techniques that I already use in my diet books, such as visualization.

Mike Cernovich’s methods include self-talk, posture improvement, mindfulness, focus, visualization, framing, and others. They will help with mindset re-set. The book is a fill-in-the-blank workbook, so buy your own copy and get to work.

The book is explicitly aimed at men. I would say the target demographic age is 16 to 40. The mind-bending methods should work for those over 40. It’s for men wanting more out of life, to rise above the hoi polloi, and willing to do the work.

It’s not a “weight loss book” per se; see the subtitle for details. However, Mr. Cernovich lost weight from 260 to 180 lb (118 to 81 kg). So he knows the struggle. He says, “…it’s almost impossible to maintain high levels of health while eating a diet high in processed foods.” I agree.

I particularly liked the chapter on money and livelihood. Young men need this information. The book is chock full of avuncular advice, so needed these days when too many boys grow up without a masculine role model. (Women, think long and hard about your children before you frivorce your husband.)

A little of the advice herein is California hippy-dippy woo, but it shouldn’t hurt you and may help, even if it doesn’t appeal to me. I’m convinced the author firmly believes in his recommendations and follows his own advice. I’m skeptical about some of the nutritional supplement advice, too; I’d check with P.D. Mangan for his thoughts.

The author hopes Gorilla Mindset becomes a perennial classic. He’s not quite there yet with this edition. He needs a chapter addressing sex/girls/women. Also, many young men need help on how to find a life purpose that motivates them. This isn’t enough: “If you feel unfilled [sic], stop doing whatever it is you’re doing. Try something else. Walk the streets until you’re exhausted. Repeat this every day. When you finally see what you want, your life will change.” My teenage daughter recently took an online occupational aptitude test that really helped give her some direction. My son is next; his interests are superficial and all over the map. Of course, aptitude is nothing without deep interest or passion. Another issue for the next edition: What about God and centuries-old religions?

A watershed moment in the Mike’s adolescence was when his father asked him, “When are you going to get serious?”

I ask you the same.

Steve Parker, M.D.

PS: If you think this review has too many words with vowels, you should see my books. They’re full of ’em.

 

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QOTD: Gravity Versus Weight Training

Average age of study subjects was 71

A good resistance training program will strengthen her bones, improve her balance, and prevent that hip fracture 60 years from now

Adult life is a battle against gravity. Weight training postpones your inevitable defeat.

—Steve Parker, M.D.

PS: If you think gravity’s a bitch, you should see how many chapters are in my books.

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Is the Vegetarian Diet Good for Diabetes?

low-carb diet, spaghetti squash, paleobetic diet, diabetic diet

These can be part of a low-carb vegetarian diet

The answer to the headline question is: Maybe.

I was surprised to learn that well-known diabetes writer David Mendosa (Type 2 DM) has switched from a very low-carb diet to a low-carb vegetarian diet, eating no more than 50 grams/day of carbohydrate. Why?

For me the issue is that I don’t want to be responsible for harming sentient beings as much as I can avoid it while still following a healthy diet.

I respect that sentiment.

I’m sure David is monitoring the effects of the diet on his blood sugars and weight. Probably his blood lipids, too.

It sounds like all David had to do was drop fish from his prior diet. He still eats eggs (whites only?), cheese, and full-fat yogurt, so I’d call him a lacto-ovo-vegetarian.

If you’re already convinced that you know the perfect diet for people with diabetes, read no further.

What Is a Vegetarian Diet?

From UpToDate.com:

Vegetarian diets vary considerably depending on the degree of dietary restrictions. According to the strictest definition, a vegetarian diet consists primarily of cereals, fruits, vegetables, legumes, and nuts; animal foods, including milk, dairy products, and eggs generally are excluded. Several less restrictive vegetarian diets may include eggs and dairy products. Some vegetarian diets may be grouped as follows:

●Macrobiotic — Vegetables, fruits, legumes, and seaweeds are included in the diet, while whole grains, especially brown rice, are also emphasized. Locally-grown fruits are recommended. Animal foods limited to white meat or white-meat fish may be included in the diet once or twice a week.
●Semi-vegetarian — Meat occasionally is included in the diet. Some people who follow such a diet may not eat red meat but may eat fish and perhaps chicken.
●Lacto-ovovegetarian — Eggs, milk, and milk products (lacto = dairy; ovo = eggs) are included, but no meat is consumed.
●Lactovegetarian — Milk and milk products are included in the diet, but no eggs or meat are consumed.
●Vegan — All animal products, including eggs, milk, and milk products, are excluded from the diet. Some vegans do not use honey and may refrain from using animal products such as leather or wool. They also may avoid foods that are processed or not organically grown.

A 2012 poll estimated that 7% of U.S. adults eat at least one meal a week that does not include meat, fish or poultry, 4% do not eat meat, fish, or poultry, and 1–2% do not eat meat, fish, poultry, dairy products, or eggs. Roughly 5% of individuals in the UK, Germany, and Australia describe themselves as vegetarian.

Switching to the paleo diet often leads to increased vegetable and fruit consumption

Are Vegetarian Diets Safe?

Vegetarians need to be careful to get enough high-quality protein, iron, vitamin B12, vitamin D, and perhaps calcium. B12 comes only from animal products, as far as I know. You can make vitamin D by exposing your skin to sufficient sunlight. Some vegetarians will need to consult a dietitian to ensure adequate nutrition. (BTW, all my comments about vegetarian diets apply to adults only—I don’t treat children, so I’m not up-to-date on their nutritional needs.)

I’ve written about vegetarian diets for diabetes before: here and here. Dr. Michael Greger couldn’t convince Dr. Harriet Hall (or me) that we should avoid eating all animal products.

The Grashow Question

Someone claiming to be Charles Grashow left a comment on one of my blogs:

As I’ve posted before, this [vegetarian macrobiotic diet] took Insulin Dependent T2D [patients] OFF MEDS within 21 days!

Seems much better – but then again this diet is vegan not paleo!

http://www.hoajonline.com/internalmedicine/2052-6954/2/3
Ma-Pi 2 macrobiotic diet intervention during 21 days in adults with type 2 diabetes mellitus, Ghana 2011

http://www.nutritionandmetabolism.com/content/11/1/39
The effect of the macrobiotic Ma-Pi 2 diet vs. the recommended diet in the management of type 2 diabetes: the randomized controlled MADIAB trial

http://www.hindawi.com/journals/jnme/2012/856342/
Medium- and Short-Term Interventions with Ma-Pi 2 Macrobiotic Diet in Type 2 Diabetic Adults of Bauta, Havana

SO – my question is this. Why do you not recommend this type of diet instead? Or does it not fit into your paradigm?

I responded:

Charles, that macrobiotic Ma-Pi 2 diet looks like it has significant potential. I quickly scanned your first link only. For those not familiar with the diet, here’s a description from your first link:

“Vegetarian Ma-Pi 2 macrobiotic diet, designed especially by Mario Pianesi for treating diabetic patients. Total volume of the Ma-Pi 2 diet consisted of 40–50% whole grains (rice, millet and barley), 35–40% vegetables (carrots, savoy cabbage, cabbage, chicory, onions, red radish, parsley), and 8% legumes (adzuki beans, chickpeas, lentils, black beans). As a complement we used gomasio (roasted ground sesame seeds with unrefined sea salt), fermented products (miso, tamari, umeboshi) and seaweeds (kombu, wakame, nori). Bancha tea (theine-free green tea) was the main liquid diet.”

“The assayed Ma-Pi 2 diet is lower in energy than the traditional one recommended for diabetic patients, but safe, with adequate satiating effect due to the high fiber content, adequate in protein (12% of the total energy), with an acceptable amino acid score, low in fat (15% of the total energy), and high in complex carbohydrates (73%). The diet has a high antioxidant capacity and a high content of bioactive compounds with recognized functional properties (Table 2). Foods were elaborated by culinary macrobiotic specialists from UPM, Italy, and offered at the hospital during breakfast, lunch, dinner and snacks. Unfortunately, the variety of vegetables was restricted because of limited availability.”

I wonder if that would be deficient in vitamin B12.

It looks like it would be worth a try for a type 2 diabetic under medical supervision (some risk of hypoglycemia). I’d like to try a few meals with those ingredients, some of which I’ve never heard of, prepared by someone who knows what they’re doing. Unless I missed it in the link, it might be hard for the average person to replicate that study diet. If I understood correctly, the study participants stayed in a hospital for three weeks and meals were prepared for them.

I don’t have time to hit the other links right now.

-Steve

My Current Stance on Vegetarian Diets For Diabetes

I say “current stance” because I’ll change my mind based on scientific evidence as it becomes available.

I’m not convinced that any of the vegetarian diets is clearly superior to the other available “diabetic diets” in terms of quality of life, longevity, and avoidance of diabetes complications.

We have some evidence that some vegetarian diets may help control diabetic blood sugars and help reduce the need for diabetes medications, at least short-term.

If my diabetic patients want to try a vegetarian diet, I have no objections as long as these criteria are met:

  • it’s a well-designed diet that provides adequate nutrition (which may require a dietitian consultation)
  • blood sugars, hemoglobin A1c, body weight, and blood lipids are monitored periodically
  • the patient is able and willing to self-monitor blood sugars fairly frequently
  • physician oversight, especially for those taking diabetes drugs

Vegetarian diets can be very high in carbohydrate content, which potentially could wreck blood sugar control. If that happens, consider a vegetarian diet with fewer starches and sugars.

Steve Parker, M.D.

PS: Did  you catch that the Ma-Pi 2 diet is “lower in energy than the traditional one recommended for diabetic patients…”? That means a reduced-calorie diet. Drop calories enough on most any diet, and you’ll likely see lower serum glucose levels, reduced triglycerides (and perhaps other lipid improvements), and loss of excess weight.

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You’re Reading a Top 10 Diabetes Blog Right Now

…at least according to Health Beeps.

I win no monetary award, blog badge, trophy, medallion, ribbon, lapel pin, nor even a stinking’ t shirt. Just braggin’ rights!

I accept the accolade wholeheartedly! Thank you Healthy Beeps.

It’s nice to get validation now and then. Sometimes I feel like a lone voice crying out in the wilderness.

Check out the other Top Tenners.

Steve Parker, M.D.

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