E-mail Interview With a Low-Carb Friendly Dietitian

Conquer Diabetes and Prediabetes, Steve Parker MD

Brain food that won’t spike blood sugars

I received an email from a registered dietitian (FS) in May, 2013. She had some reasonable questions for me and I thought you might be interested in my answers. Here’s her email first:

So funny that you happened to comment on my blog post today because I’d already planned to email you. I’m writing an article on low-carbohydrate diets for Diabetes Self Management magazine and was hoping to ask you a few questions about your experience treating your patients with the Diabetic Mediterranean and Ketogenic diets. We could do it via e-mail if you like. What I’d really like to know is how many of your patients were/are successful in sticking to the diet long term and what type of feedback you’ve received from them, along with any other information you feel is pertinent. Also, what carb range to you recommend for your diabetic patients?

My response:

Dear F,

First, let me explain a little about my medical practice. I’m a full-time hospitalist, meaning I treat adult patients only in the hospital setting. Nearly all of my patients come in through the emergency department. I treat a great variety of problems, like pneumonia, heart failure, cellulitis, pancreatitis, urinary tract infections, headaches, strokes, GI tract bleeding, cholecystitis, altered mental status, out of control diabetes, etc. My training is in Internal Medicine.

By the way, I work in Scottsdale, Arizona, which is a fairly sophisticated and affluent community. My two hospitals employ some dietitians who receptive to very-low-carb eating.

As it turns out, 30% of my hospitalized patients happen to have diabetes, at least 95% of which is type 2. This is typical for non-pediatric hospitalists. Nearly all of these diabetics have an established diagnosis of diabetes and a relationship with an outpatient doctor who is treating it. I usually ask them, “Are you on any special diet, or do you pretty much eat whatever you want?” Half of them say “nothing special; I eat what I want”! Three out of 10 respond that they “avoid sweets and desserts” or something similar. One or two of every 10 report they make a strong effort to reduce carb consumption below the usual American level (250-300 g/day). No more than five of every 100 has ever heard of Dr. Richard Bernstein’s Diabetes Solution. (I consider Dr. B the founder and leader of the modern carbohydrate-restricted diabetes diet movement.) No more than one of every 100 follows Dr. Bernstein’s or a similar very-low-carb or ketogenic diet.

Once these patients leave the hospital, I cannot follow them in a clinic setting. I wish I could. I see many of them in the hospital only once, which is not much time to develop a trusting relationship. Perhaps surprisingly, I don’t often do a “hard sell” for a low-carb diet, even though that’s what I’d follow if I had diabetes of either type. People have to be ready to make a change in hard-wired eating behavior, like an alcoholic is ready to quit drinking only when he’s hit “rock bottom.” For someone with diabetes, that rock bottom point is typically at the time of initial diagnosis or when a major complication hits (such as neuropathy, kidney impairment, or retinopathy). They’re more receptive to change then. All of my hospitalized diabetics get a business card referring them to my Low-Carb Mediterranean Diet website (Diabetic Mediterranean Diet).

Since I have no outpatient clinic, I have no way of knowing how many of them adopt a low-carb way of eating. I do get unsolicited emails from diabetics who have adopted the Low-Carb Mediterranean Diet or Ketogenic Mediterranean Diet, and they report satisfying results with weight management and glucose control. Problem is, as mentioned, I don’t know the denominator. Not once in two years has anyone ever contacted me to report they were harmed by the diets or that they didn’t help at all with glucose control.

I’m convinced you can get good nutrition eating low-carb and very-low-carb. By “low-carb,” I mean under 130 g/day, and “very-low-carb” is under 50 or so. An added benefit for diabetics is that they may be able to avoid the cost and toxicity of some diabetes drugs. We have no long-term toxicity data on most of our diabetes drugs. (Insulin and metform are safe long-term.)

Whether a diabetic goes with Dr. Bernstein’s, my Low-Carb Mediterranean Diet, or Dr. Atkins’ Diabetes Revolution, I think they’re going to be better off over the long run compared to eating a typical “diabetic” diet that has 200+ grams of net carbs. Of course, I have no hard proof. We may never have it. Of those who choose LCMD, I have no data on how many of them actually follow it long-term. Hey, I finally answered one of your questions!

If one of my diabetics prefers to eat Bernstein or Atkins-style over my program, I have no problem with that at all. (The Atkins program recommends some nutritional supplements that I’m not convinced are necessary or even minimally helpful.)

How many diabetics stick with a carb-restricted diet (e.g., under 130 g/day) long-term, more than 2-3 months? My guesstimate is only two or three out of ten. The problem is that we live in a highly carb-centric culture: temptation abounds, we form firm dietary habits in childhood, carbs are cheap, and, frankly, many taste very good.

Incidentally, I don’t have diabetes but I strive to keep my digestible (or net) carbs in the range of 60 to 80 grams/day. The carb restriction helps me control my weight, and I’m seeing some preliminary evidence that it may help with prevention of dementia and mild cognitive impairment.

The long-term carbohydrate intake range I recommend for diabetics is 60-80 g of net or digestible carb daily. Twenty or 30 g/day (a la Bernstein or my Ketogenic Mediterranean Diet) can help overweight diabetics lose the excess fat a little quicker and easier. But 30 d/day over the long run is extremely difficult for all but the most highly motivated. If I had type 1 diabetes, I’d give 30 g/day a serious try, like Dr. Bernstein. Competitive endurance athletes may need more than 100 g/day. Some mild type 2’s may be able to adequately handle over 80 g/day depending on degree of residual pancreas beta cell function. It bothers me to see a type 2 diabetic taking 4-5 diabetes drugs just so they can control diabetes while eating a high-carb diet (e.g., over 200 g/day). Again, we don’t know the long-term effects of most of these drugs.

I’m sorry for being so long-winded! I hope this helps. Email me soon if you have more questions and I’ll respond w/in 24h. Or call me at xxx-xxx-xxxx. Please keep up the good work. In turn, I’ll keep doing my little part to turn around this carb-centric culture. At least until the science dictates otherwise.

Sincerely,

-Steve

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Filed under Carbohydrate, ketogenic diet, Mediterranean Diet, Prediabetes

GRADE Trial Hopes to Identify Best Drugs for Type 2 Diabetes

Click for details.  Unfortunately, it will years before we have the results. In the meantime, consider the Low-Carb Mediterranean Diet.

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Pancreas Beta Cells May be Key to the Cause of Type 2 Diabetes

…according to an article I found in Diabetes Care. As background, be aware that one theory holds that T2 diabetes is caused primarily by body tissue insulin resistance, separate from what’s going on in the pancreas beta (β) cells that produce insulin to control blood sugar.

Some quotes:

Although it has long been assumed that insulin resistance is the leading factor in the pathogenesis of type 2 diabetes, evidence for the importance of the pancreatic β-cells has accumulated over the past decades. In fact, the vast majority of genes associated with type 2 diabetes have been linked to the β-cell, and impairments in β-cell mass and in insulin secretion have been reported in numerous studies in patients with type 2 diabetes.

***

It has also been suggested that obesity causes type 2 diabetes through impaired insulin action. Undoubtedly, the risk of developing type 2 diabetes increases markedly with BMI. However, if obesity were really the cause of type 2 diabetes, one would expect the vast majority of obese individuals to develop hyperglycemia, whereas in reality ∼80% of obese individuals remain free of diabetes. These findings suggest that obesity and insulin resistance are indeed important cofactors that increase the individual risk of diabetes but that the actual cause of the disease seems to be clearly linked to the β-cells.

***

The conundrum of whether loss of mass or loss of function underlies the β-cell defects in type 2 diabetes is not likely to be conclusively solved on the basis of the evidence we have reviewed here. Decreased cell mass and acceleration of the biological processes resulting in β-cell loss have been described in type 2 diabetes by a number of laboratories. On the other hand, several lines of evidence suggest that β-cell functional defects may exist in type 2 diabetes.

Both viewpoints tacitly assume that 1) type 2 diabetes is a rather homogeneous entity, at least when it comes to β-cell biology, and 2) overall islet secretory capacity is a linear function of the product between β-cell number and isolated β-cell function. It is possible that neither assumption holds true.

The most likely scenario, indeed, is that a variable combination of the two processes, loss of mass and loss of function, is at work in type 2 diabetes. Indeed, there appears to be a tight relationship between mass of pancreatic β-cells and functional insulin secretion.

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Another Research Report Links Type 2 Diabetes With Dementia

Compared with non-diabetics in the study, T2s had brain atrophy  (shrinkage on MRI scans) and cognitive deficits reminiscent of pre-clinical Alzheimer’s disease.

Click for details at Diabetes Care.

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Alcohol Consumption Linked to Lower Risk of Death and Kidney Disease in Type 2 Diabetics

…according to an article at MedPageToday. Over 6,000 T2 diabetics were followed for over five years.

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Deteriorating Brain Function Linked to High Insulin Levels and Insulin Resistance: Here’s How You Fight Back

dementia, memory loss, Mediterranean diet, low-carb diet, glycemic index, dementia memory loss

Don’t wait to take action until it’s too late

Insulin resistance and high blood insulin levels promote age-related degeneration of the brain, leading to memory loss and dementia according to Robert Krikorian, Ph.D.  He’s a professor in the Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati Academic Health Center.  He has an article in a recent issue of Current Psychiatry – Online.

Proper insulin signaling in the brain is important for healthy functioning of our brains’ memory centers.  This signaling breaks down in the setting of insulin resistance and the associated high insulin levels.  Dr. K makes much of the fact that high insulin levels and insulin resistance are closely tied to obesity.  He writes that:

“Waist circumference of ≥100 cm (39 inches) is a sensitive, specific, and independent predictor of hyperinsulinemia for men and women and a stronger predictor than body mass index, waist-to-hip ratio, and other measures of body fat.”

Take-Home Points

Dr. Krikorian thinks that dietary approaches to the prevention of dementia are effective yet underutilized.  He mentions reduction of insulin levels by restricting calories or a ketogenic diet: they’ve been linked with improved memory in middle-aged and older adults.

Dr. Krikorian suggests the following measures to prevent dementia and memory loss:

  • eliminate high-glycemic foods like processed carbohydrates and sweets
  • replace high-glycemic foods with fruits and vegetables (the higher polyphenol intake may help by itself)
  • certain polyphenols, such as those found in berries, may be particularly helpful in improving brain metabolic function
  • keep your waist size under 39 inches, or aim for that if you’re overweight

I must mention that many, perhaps most, dementia experts are not as confident  as Dr. Krikorian that these dietary changes are effective.  I think they probably are, to a degree.

The Mediterranean diet is high in fruits and vegetables and relatively low-glycemic.  It’s usually mentioned by experts as the diet that may prevent dementia and slow its progression.

Read the full article.

I’ve written before about how blood sugars in the upper normal range are linked to brain degeneration.  Dr. Krikorian’s recommendations would tend to keep blood sugar levels in the lower end of the normal range.

Steve Parker, M.D.

PS: Speaking of dementia and ketogenic, have you ever heard of the Ketogenic Mediterranean Diet?  (Free condensed version here.)

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Filed under Carbohydrate, Dementia, Glycemic Index and Load, ketogenic diet

Low-Carb Breakfast: Brian’s Berry Breakfast

paleobetic diet, breakfast, paleo diet

Brian’s Berry Breakfast

My stepson came up with this one. Thanks, dude! If you think breakfast means eating out of a bowl, this one fits the bill.  And talk about easy!

Ingredients:

  • 4.5 oz (127 g) fresh strawberries, diced into small pieces
  • 2 oz (58 g) walnuts, crumbled by hand

Mix ingredients together in a bowl and enjoy eating with a spoon while your tablemates eat Neolithic Cheerios.

Nutritional analysis:

  • 76% fat
  • 16% carbohydrate
  • 8% protein
  • 410 calories
  • 17 carb grams
  • 6.2 g fiber
  • 10.9 g digestible carb
  • prominent features: 80% of vitamin C RDA (recommended dietary allowance), 32% of RDA for phosphorus, 27% of RDA for iron, 25% of RDA for magnesium, 21% of RDA for vitamin B6, 19% of RDA for thiamine.  It’s also particularly rich in copper and manganese.

—Steve

PS: Nutritional analysis by free software at FitDay.com

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Franziska Spritzler Explains Why So Many Dietitians Are Against Low-Carb Diets

Click for details. Briefly:

1. They think it’s dangerous. 
2.They believe the diet-heart hypothesis. 
3. They think the diet is unbalanced.  
4. They think no one will follow it long term.

Franziska debunks these ideas one by one.

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Dr. Georgia Edes Raves About Her Ketogenic Diet Experience

Click for details. Here’s her version of a ketogenic diet:

My diet consists almost entirely of roasted chicken (with skin), duck (with skin), duck fat, turkey, fish, chicken liver, zucchini, spinach, plantain chips, berries, lettuce, small amounts of black coffee, and salt.  I’ve been avoiding chocolate entirely.   Every once in a while I eat beef, pork, or a very small amount of cheese, or when at a restaurant might order something that includes a cream, wine, or butter-based sauce, but these don’t usually agree with me, so I keep them to a minimum, and most days I completely avoid them.  I steer clear of preserved, smoked, cured, aged, fermented, canned, and processed foods whenever possible.

Most folks will enter ketosis when they get their daily digestible carbohydrate consumption below 30-50 grams. My favorite method is the Ketogenic Mediterranean Diet.

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Is Exercise Twice a Week as Good as Six Sessions?

exercise for weight loss and management, dumbbells

If you’re not familiar with weight training, a personal trainer is an great idea

Weight Maven Beth Mazur  found evidence in favor of the fewer days, at least in post-menopausal women.

I don’t like to exercise. Sometimes I find excuses to avoid even my twice weekly 40-minute workouts. I do enjoy hiking; I even hiked to the bottom of the Grand Canyon and back out last May. But that’s not exercise, it’s more recreation.

You may well have good reasons to exercise every day. Maybe you’re a competitive athlete or enjoy exercise. If you just want the health benefits of exercise, I’m increasingly convinced that twice a week is enough.

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