This will bore most readers.
I just want to mention a scientific review article from 2009 that reviews insulin activity (down to a molecular level) in the context of type 2 diabetes, atherosclerosis, and insulin resistance. Towards the end it starts sounding like an informercial for thiazolidinedione drugs.
The author makes a great case for the dangers of hyperinsulinemia.
Good reference overall.
R. A. DeFronzo wrote “Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009.” Diabetologia, 2010 (53); 1,270-1,287. doi: 10.1007/s00125-010-1684-1