One-Third of Healthy-Weight U.S. Adults Over 45 Now Have Prediabetes

Prediabetes can be defined as having hemoglobin A1c, a blood test, of 5.7 to 6.4%. We usually consider accumulation of fat around the abdomen to be a risk factor for prediabetes and type 2 diabetes. The study at hand (link below) didn’t find this to be the case in adults who were at a “healthy weight” defined as Body Mass Index of 18.5 to 24.9.

For this population, we need to identify other modifiable factors that predispose to type 2 diabetes, such as physical inactivity, lack of muscle mass, poor diet, and environmental toxins.

“PURPOSE Trends in sedentary lifestyle may have influenced adult body composition and metabolic health among individuals at presumably healthy weights. This study examines the nationally representative prevalence of prediabetes and abdominal obesity among healthy-weight adults in 1988 through 2012.”

Source: Prevalence of Prediabetes and Abdominal Obesity Among Healthy-Weight Adults: 18-Year Trend

PS: To prevent prediabetes from transmogrifying to diabetes, click here.


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Higher risk of cancer before and after diabetes diagnosis 

The lifetime probability of an individual developing invasive cancer in the U.S. is about 4 in 10 (40%). A little higher in men (45%), a little lower in women (38%).

The good news is that cancer death rates in the U.S. have dropped over the last 20 years. The reduction is 18% for men and 10% for women.

The bad news is that the American Cancer Society projects around 600,000 yearly deaths from cancer in the U.S.

If we look at deaths of people under 85, cancer kills more people than heart disease.

In men, 25% of all invasive cancers will be prostate cancer. In women, breast cancer is the leader, comprising 26% of all cancers. (Common skin cancers are rarely invasive or fatal and are not included in these statistics. Melanoma, on the other hand, is invasive and dangerous.)

New research indicates that people with diabetes may be more prone to several cancers. Older research says men with diabetes are less likely than average to get prostate cancer. Don’t ask me why.

Medical News Today provides a few details:

People who have diabetes may have a higher chance of developing cancer either before or immediately after receiving a diagnosis of diabetes, according to a study published online in the American Cancer Society’s journal, Cancer.

Additional healthcare when people receive a diagnosis of diabetes may lead to more cancer diagnoses around the same time.The results indicate that there is a need for better understanding of the association between cancer and diabetes.

Previous studies have suggested that people with type 2 diabetes have a higher risk of developing several different types of cancer.

Source: Higher risk of cancer before and after diabetes diagnosis – Medical News Today

Steve Parker, M.D.

PS: The traditional Mediterranean diet protects against cancer. We don’t know if my versions of it are even better at preventing cancer.

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Professor Tim Noakes Explains Why He Favors a Low-Carb Diet for Diabetes

Click the link below for details.

Overall, Prof. Noakes makes a lot of sense. I like the concept of diabetes as a disease of carbohydrate intolerance. He may not have everything right. For instance, experts debate whether insulin resistance is a cause or result of type 2 diabetes.

The professor writes:

“My interest in the dietary management of diabetes stems from watching my father’s rapid downward physical decent in the years after he was diagnosed with Type 2 diabetes mellitus (T2DM); the diagnosis of T2DM in myself; and my reading of the “alternative” literature which convinces me that T2DM does not have to be an inevitably progressive disease:My conclusion is that unlike my father, it is not my pre-ordained fate to die from the final common pathway in fatal T2DM – disseminated obstructive arterial disease. But to achieve that I will have to ignore what I was taught and which, in turn, I have conveyed to two generations of students:So to prevent the development of the disseminated obstructive arterial disease of T2DM, I will have to follow dietary practices that are the polar opposite of those my father was advised to adopt and which hastened his death; advice that I personally practised for 33 years and which ultimately caused me also to develop T2DM.”


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Recipe: Gazpacho – A taste of Andalusia

These are Hass or California avocados (the other common one in the U.S is the Florida avocado)

These are Hass or California avocados (the other common one in the U.S is the Florida avocado)

Here’s a recipe from The Low Carb Diabetic blog, one of my favorites. No carb count is provided but I bet it’s relatively low. If you know the carb count per serving, share in the comments. Calculate the carbs yourself at FitDay. Click the link below for the recipe. It’s paleo-diet compliant, if you don’t mind vinegar. A snippet:

“Gazpacho is a soup made of raw vegetables and served cold, usually with a tomato base, originating in the southern Spanish region of Andalucia, which some spell with a c, while others use an s! This soup can be great for a hot day when making a lunch that takes just a few minutes is exactly what you want. In our version of this Andalusian peasant dish we leave out the soaked bread and instead use a creamy avocado to give it substance.”

Source: The Low Carb Diabetic: Gazpacho – A taste of Andalucia

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Endocrinologists Hesitant to Believe Empagliflozin Reduces Cardiac Events and Deaths

Larry Husten covers the issue at his blog. Click the link below for details. I’m in the endocrinology camp on this one. A quote from Mr. Husten’s post:

“An observer came away from the meeting with the strong impression that the endocrinologists did not want to accept any evidence that empagliflozin could reduce the risk of cardiovascular death; were not prepared to acknowledge that drugs might work in diabetes by effects that were independent of blood glucose; and wanted to be left in peace to be allowed to micromanage hemoglobin A1c without being reminded that doing so does not change the cardiovascular risk of patients with diabetes.”

Source: Prominent Cardiologists Decry Tepid Support For Empagliflozin By Endocrinologists


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The Low Carb Diabetic: Roasted Jubilee tomatoes with a fresh herb crust

Try growing your own...

Try growing your own…

Tomatoes are a time-honored component of the Mediterranean diet. Their lycopenes and other phytonutrients may help preserve prostate health. Heres a recipe, with carb counts provided, from The Low Carb Diabetic:

“These tomatoes, when topped with a herby breadcrumb mixture, make a very nice starter or side dish. If you do not wish to use breadcrumbs, a substitute such as toasted pine nuts could be used instead…”

Source: The Low Carb Diabetic: Roasted Jubilee tomatoes with a fresh herb crust


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Are Computers Sapping Your Brain?

Thinking about it...

Exercise your brain

I saw a patient at the hospital a couple years ago who had been brought in by ambulance after suffering some trauma (not to his brain). He couldn’t call any friends or relatives to let them know what was going on because he didn’t have his cellphone. His phone had all his contact numbers so he had no reason to memorize any. Would you be in the same boat?

DailyMail has an interesting article on whether our use of technology is making us dumber. If we turn over mental tasks like navigation and math to computers, do our brains waste away? Is this how the robots take over? Will we be seeing more and earlier cases of age-related dementia? E-mentia?

This is worth keeping an eye on.

Steve Parker, M.D.

PS: The five other members of my household all have cellphones. The only number I’ve memorized is my wife’s.

low-carb mediterranean diet

Front cover of book

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