Diabetes Drug Semaglutide Promotes Weight Loss

“Should I wait for FDA approval?”

I met a patient at the hospital recently who was taking semaglutide. I asked how long he had diabetes and he told me he didn’t have diabetes: his PCP (primary care physician) was prescribing it for weight loss.

A recent study enrolled 1,961 obese non-diabetics and found a very significant weight loss difference compared to the placebo group. I expect Novo Nordisc will be asking for FDA approval to market semaglutide, originally for diabetes, as a weight-loss drug. But what happens after you quit taking the drug? I bet you know.

In participants with overweight or obesity, 2.4 mg of semaglutide [injected] once weekly plus lifestyle intervention was associated with sustained, clinically relevant reduction in body weight.

Source: Once-Weekly Semaglutide in Adults with Overweight or Obesity | NEJM

Steve Parker, M.D.


Filed under Drugs for Diabetes, Weight Loss

3 responses to “Diabetes Drug Semaglutide Promotes Weight Loss

  1. Interesting it must help the body uses fat for energy I would think.

  2. Such an interesting discovery to look into. I have been looking for methods to cut weight and of all the options I had I found that green tea is the best and showed great results. It helps in increasing the metabolic rate activity in the body hence burning extra calories in the body hence contributes to natural weight loss.