The American Heart Association and American Diabetes Association just published a review paper on nonnutritive sweeteners, also known as low-calorie sweeteners, artificial sweeteners, noncaloric sweeteners, and intense sweeteners. I quote from the conclusion section:
At this time, there are insufficient data to determine conclusively whether the use of NNS to displace caloric sweeteners in beverages and foods reduces added sugars or carbohydrate intakes, or benefits appetite, energy balance, body weight, or cardiometabolic risk factors.
With regard to nonnutritive sweeteners and glycemic response [in diabetics], 4 randomized trials that varied from 1 to 16 weeks in duration found no significant difference between the effects of nonnutritive sweeteners and various comparisons (sucrose, starch, or placebo) on standard measures of glycemic response (i.e., plasma glucose and insulin, HbA1c, C-peptide) and, in general, did not detect clinically relevant effects.
You’re welcome to read the entire document.
-Steve
Diabetic Mediterranean Diet 
“With regard to nonnutritive sweeteners and glycemic response [in diabetics], 4 randomized trials that varied from 1 to 16 weeks in duration found no significant difference between the effects of nonnutritive sweeteners and various comparisons (sucrose, starch, or placebo) on standard measures of glycemic response (i.e., plasma glucose and insulin, HbA1c, C-peptide) and, in general, did not detect clinically relevant effects.”
Does anybody believe this? You don’t need a randomized controlled trial to know that this can’t be right? One could imagine that an experiment where they were able to make this come out right but surely this is nonsense, no?
Dr. Feinman, that does seem incredible.
Hmmm…. Maybe the ADA should take a closer look at this research.
http://care.diabetesjournals.org/content/32/4/688