The U.S. Food and Drug Administration a few days ago announced its approval of Juvisync for treatment of type 2 diabetes. It’s just a combination of sitagliptin and simvastatin, drugs that have been on the market for years. Simvastatin isn’t a diabetes control drug at all; it’s a cholesterol-lowering drug in the statin class.
I often see patients with potential drug side effects. If they’re taking six drugs, the culprit is usually only one of the drugs. So I tell the patient to put that one drug on hold and see what happens. Combination drugs interfere with that strategy, so I tend to avoid them.
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Isn’t the rationale’ behind these combo drugs is often that they can be patented, and then advertised to us, so we will come into your office and say “Should I be on that new Juvisync instead of my sitagliptin? I saw that comedy actress takes it now.”
hostkabob, I’m not sure about that patent issue; you may well be right. I do know the drug compnanies will commonly take a regular drug they own, then modify the molecule or delivery system to turn the drug into a sustained-release preparation. That also extends the patent.
Another thought I have is that statin drugs are over-prescribed. Patients should talk to their doctors to make sure they’re likely to benefit from the drug.
-Steve
I suspect that there will be a big cost disadvantage in using Juvisync for treatment of type 2 diabetes.
Richard A., I agree.